Thermo Fisher Scientific NGF-Receptor (p75)/CD271 Monoclonal Antibody (NGFR, 1964)
인간 NGF 수용체(p75/CD271)를 인식하는 Mouse monoclonal antibody입니다. IHC(P) 및 Peptide Array에 사용 가능하며, Protein A/G로 정제된 액상 형태입니다. 신경세포의 분화 및 생존 연구에 적합합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | NGFR, 1964 |
| Immunogen | Recombinant fragment of human p75 NGFR protein (around aa 281–421) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- For IHC (PFA-fixed): Incubate antibody for 30 minutes at room temperature.
- Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
Neurotrophic factors regulate the survival, differentiation, and maintenance of neurons in both the peripheral and central nervous systems, as well as other neural crest-derived cell types. Developing sympathetic neurons depend on nerve growth factor (NGF) during the period of target competition in vivo.
Antibodies specific to NGFR p75 are valuable tools for detecting and characterizing NGFR p75, aiding in the study of neural development, plasticity, and repair mechanisms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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