Thermo Fisher Scientific NGF-Receptor (p75)/CD271 Monoclonal Antibody (NGFR, 1964)
인간 NGF 수용체(p75/CD271)를 인식하는 마우스 단클론 항체로, 면역조직화학(IHC) 및 펩타이드 어레이에 적합합니다. 단백질 A/G로 정제된 액상 항체이며 보존제가 없습니다. 신경세포 발달, 분화, 재생 연구에 유용합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | NGFR, 1964 |
| Immunogen | Recombinant fragment of human p75 NGFR protein (around aa 281–421) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | −20°C or −80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed): incubate antibody for 30 min at room temperature (RT).
- Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C, followed by cooling at RT for 20 minutes.
Target Information
Neurotrophic factors regulate the survival, differentiation, and maintenance of neurons in both peripheral and central nervous systems, as well as other neural crest-derived cells.
Developing sympathetic neurons depend on nerve growth factor (NGF) during the period of target competition in vivo.
Antibodies specific to NGFR p75 are valuable tools for detecting and characterizing NGFR p75, aiding studies on neuronal development, plasticity, and repair mechanisms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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