Thermo Fisher Scientific NGF-Receptor (p75)/CD271 Recombinant Rabbit Monoclonal Antibody (NGFR, 1997R)
NGFR (CD271) 단백질을 표적하는 Thermo Fisher의 재조합 토끼 단일클론 항체입니다. 인간 및 비인간 영장류 반응성, IHC(P) 및 Peptide Array에 적합합니다. Protein A/G 정제, PBS 용액 형태로 제공되며 보존제 무첨가입니다.
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Thermo Fisher Scientific NGF-Receptor (p75)/CD271 Recombinant Rabbit Monoclonal Antibody (NGFR, 1997R)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | NGFR, 1997R |
| Immunogen | Recombinant human full-length p75 NGFR protein (target family: NGFR (CD271), UniProt ID: P08138-1, antigen range: 1–427) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- This antibody does not react with Mouse or Rat.
- For Immunohistochemistry (PFA-fixed): incubate antibody for 30 minutes at room temperature.
- Staining of formalin-fixed tissues requires heating sections in 10 mM Tris with 1 mM EDTA (pH 9.0) for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
Neurotrophic factors regulate the survival, differentiation, and maintenance of neurons in both peripheral and central nervous systems, as well as other neural crest-derived cell types. Developing sympathetic neurons depend on nerve growth factor (NGF) during target competition in vivo. Antibodies specific to NGFR p75 are valuable tools for detecting and characterizing NGFR p75, contributing to research on neuronal development, plasticity, and repair.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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