Thermo Fisher Scientific NGF-Receptor (p75)/CD271 (Soft Tissue Tumor Marker) Recombinant Rabbit Monoclonal Antibody (NGFR/8590R)

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG, kappa

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

NGFR/8590R

Immunogen

Recombinant human full-length p75 NGFR protein if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:NGFR (CD271),uniProtId:P08138-1,ncbiNodeId:9606,antigenRange:1-427,antigenLength:427,antigenImageFileName:4804-RBM12-P0_NGFR_CD271_P08138-1_Rabbit.svg,antigenImageFileNamePDP:4804-RBM12-P0_NGFR_CD271_P08138-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

200 µg/mL

Purification

Protein A/G

Storage buffer

PBS with 0.05% BSA

Contains

0.05% sodium azide

Storage conditions

4° C

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Positive Control: and ganglionic satellite cells. Melanomas. and perineural cells of peripheral nerves Neurofibroma. Soma and axons of sensory neurons Neuronal axons or tumors of nerve sheath differentiation e.g. Schwannoma Schwann cells

Cellular Location: Cell Surface. Cytoplasm.

Target Information

Neurotrophic factors control the survival, differentiation and maintenance of neurons in the peripheral and central nervous systems, and of other neural crest-derived cell types. Developing sympathetic neurons are absolutely dependent upon nerve growth factor (NGF) during the period of target competition in vivo. Antibodies reacting specifically with NGFR p75 are useful tools in the detection and characterization of NGFR p75, to enhance our understanding of a wide range of phenomena in the development, plasticity and repair of the nervous system.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.