Thermo Fisher Scientific NGF-Receptor (p75)/CD271 Monoclonal Antibody (NGFR, 1964)
인간 NGFR(p75)/CD271을 인식하는 Mouse IgG2b 단클론 항체로, IHC(P) 및 Peptide Array에 사용 가능. 신경 성장 인자 수용체 연구에 적합하며, 액상 형태로 제공. 4°C 보관, Protein A/G 정제.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1–2 µg/mL
Peptide Array (Array)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | NGFR, 1964 |
| Immunogen | Recombinant fragment of human p75 NGFR protein (around aa 281–421) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Immunohistochemistry (PFA fixed): incubate antibody for 30 min at room temperature.
Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
Neurotrophic factors control the survival, differentiation, and maintenance of neurons in the peripheral and central nervous systems, as well as other neural crest-derived cell types.
Developing sympathetic neurons are dependent upon nerve growth factor (NGF) during target competition in vivo.
Antibodies specific to NGFR p75 are valuable tools for detecting and characterizing NGFR p75, aiding in studies of nervous system development, plasticity, and repair.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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