Thermo Fisher Scientific PPP2R5D Monoclonal Antibody (OTI5E7), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:150

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

Zinc-finger proteins contain DNA-binding domains and perform various transcriptional activation or repression functions.
ZNF265 (Zinc finger protein 265), also known as ZRANB2, ZIS, ZIS1, or ZIS2, is a 330 amino acid protein of the ZRANB2 family localized in the nucleus.
It acts as a splicing factor responsible for alternatively splicing Tra-2 beta transcripts and may interfere with constitutive 5'-splice selection.
ZNF265 has two RanBP2-type zinc fingers mediating RNA-binding activity. Two isoforms (ZIS-1 and ZIS-2) are expressed through alternative splicing.
Upon DNA damage, ZIS-2 may be phosphorylated by ATM or ATR.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.