Thermo Fisher Scientific Thyroglobulin Recombinant Rabbit Monoclonal Antibody (TGB, 1968R)
인간 Thyroglobulin을 인식하는 재조합 토끼 단클론 항체로, 면역조직화학(IHC)용으로 최적화됨. HEK293 세포 발현, Protein A/G 정제, 액상 형태로 제공. 항-티로글로불린 자가항체 연구 및 갑상선 질환 연구에 적합.
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Thermo Fisher Scientific Thyroglobulin Recombinant Rabbit Monoclonal Antibody (TGB, 1968R)
Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | TGB, 1968R |
| Immunogen | Recombinant full-length human Thyroglobulin protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed): Incubate antibody for 30 min at room temperature.
- Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C, followed by cooling at room temperature for 20 min.
Target Information
Human thyroglobulin (hTg) is a high molecular weight glycoprotein (605 kDa) found in thyroid follicular cells.
It plays a key role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones T4 and T3.
Anti-thyroglobulin autoantibodies are associated with autoimmune thyroid diseases such as Hashimoto thyroiditis and Graves disease, with the highest levels observed in Hashimoto thyroiditis.
Anti-hTG is also characteristic of thyroid cancer and can be used in the follow-up of cancer patients.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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