Thermo Fisher Scientific TGF-alpha (Transforming Growth Factor alpha) Monoclonal Antibody (MF9)
TGF-alpha 단백질을 인식하는 MF9 클론의 Mouse Monoclonal Antibody. 다양한 종(Bovine, Human, Mouse, Rat)에 반응하며 IHC, ICC/IF, ELISA 등 여러 응용에 사용 가능. 고순도 Protein A/G 정제, 1 mg/mL 농도의 액상 시약으로 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 2–4 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| ELISA | 2–4 µg/mL |
Product Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Bovine, Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MF9 |
| Immunogen | A 17-amino acid synthetic peptide from the carboxyl-terminus of rat TGF-alpha |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
TGF-alpha is an EGF-related polypeptide growth factor that signals through the EGF receptor and stimulates proliferation of epidermal and epithelial cells. It is produced by monocytes, keratinocytes, and various tumor cells, and induces anchorage-independent transformation in cultured cells. Human, murine, and rat TGF-alpha are cross-species reactive. TGF-alpha (aa 50) has 33% homology to EGF, binds to EGFR, activates receptor tyrosine phosphorylation, and promotes cell proliferation. It plays a role in tumor initiation by inducing a reversible transformed phenotype.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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