Thermo Fisher Scientific Thyroglobulin Recombinant Rabbit Monoclonal Antibody (TGB, 1968R)
Recombinant rabbit monoclonal antibody against Thyroglobulin (TGB, clone 1968R). Validated for IHC-P applications in human samples. High specificity and reproducibility with Protein A/G purification. Provided as a liquid form, 200 µg/mL concentration, ...
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Applications
Tested Application
- Immunohistochemistry (Paraffin) (IHC-P)
Tested Dilution
- 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | TGB, 1968R |
| Immunogen | Recombinant full-length human Thyroglobulin protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- For immunohistochemistry (PFA fixed): incubate antibody for 30 minutes at room temperature.
- Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
Human thyroglobulin (hTg) is a high molecular weight glycoprotein (605 kDa) found in thyroid follicular cells. It plays a key role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones (T4 and T3).
Thyroid disorders are often autoimmune in origin, and anti-thyroglobulin autoantibodies are present in all thyroid autoimmune diseases (Hashimoto thyroiditis, Graves disease), with the highest levels in Hashimoto thyroiditis.
Anti-hTG is also characteristic of thyroid cancer and can be used for patient follow-up.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: Thyroglobulin antigen diagram 및 관련 시각 자료)
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