Thermo Fisher Scientific PSMA4 Monoclonal Antibody (OTI5D8), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:2,000

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:150

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure, composed of four rings of 28 non-identical subunits (two alpha and two beta rings). Proteasomes are abundant in eukaryotic cells and cleave peptides in an ATP/ubiquitin-dependent, non-lysosomal pathway. The immunoproteasome variant processes class I MHC peptides.
The PSMA4 gene encodes a 20S core alpha subunit belonging to the peptidase T1A family. Three alternatively spliced transcript variants encoding different isoforms have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.