Thermo Fisher Scientific WIZ Polyclonal Antibody
WIZ 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체. Western blot과 Flow cytometry에 사용 가능하며, 인간 반응성 및 마우스·랫 예측 반응성. 합성 펩타이드 면역원 기반, 액상 형태로 -20°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 0.3–1 µg/mL
Flow Cytometry (Flow)
- Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (RSYIQGGRPFTKKFR) corresponding to the internal amino acids of WIZ (aa 1453–1468) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10979973 |
Product Specific Information
- This antibody is predicted to react with mouse and rat based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 2,000.
Target Information
WIZ, also known as ZNF803, was initially identified in a mouse cerebellum cDNA library screen and its expression was found in the granule cell layers of the cerebellum, dentate gyrus, and olfactory bulb. Later studies indicate that WIZ is ubiquitously expressed.
WIZ is a nuclear protein that co-localizes with G9a, a histone methyltransferase responsible for mono- and dimethylation of H3K9 at euchromatic regions. It can also associate with CtBP family proteins, known transcriptional co-repressors, and may link G9a/GLP complexes to CtBP co-repressor machinery, regulating complex stability and gene silencing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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