Thermo Fisher Scientific STING1/TMEM173 Monoclonal Antibody (STING1/7435)
STING1/TMEM173 단백질을 인식하는 Mouse monoclonal antibody. Western blot 및 IHC(P, PFA)에서 검증됨. 단백질 A/G로 정제된 액상 형태, 보존제 무첨가. 선천면역 신호전달 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | - |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | STING1/7435 |
| Immunogen | Recombinant fragment (aa 190–290) of human TMEM173 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Target Information
STING (Stimulator of Interferon Genes) is a 379 amino acid signaling protein that plays a critical role in innate immune signaling. It activates NF-kappa-B and IRF3 transcription pathways to induce type I interferon (IFN-α and IFN-β) expression, establishing an antiviral state. STING may also function as a translocon, influencing type I interferon induction and apoptotic signaling through its association with MHC-II. It is localized in the endoplasmic reticulum membrane, cell membrane, and mitochondrial outer membrane and is expressed ubiquitously across tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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