Thermo Fisher Scientific IL-2 Monoclonal Antibody (419A7A3)
인간 IL-2를 인식하는 Mouse monoclonal antibody로, WB 및 ELISA에 사용 가능. Sandwich ELISA의 capture antibody로 권장되며, Protein A로 정제된 액상 형태. 1 mg/mL 농도, PBS(pH 7.4)에 보관하며 4°C에서 안정적 저장 가능.
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Applications
Western Blot (WB)
- Tested Dilution: Not specified
- Publications: View 1 publication
ELISA
- Tested Dilution: Assay-dependent
- Publications: View 2 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 419A7A3 |
| Immunogen | Purified recombinant human IL-2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.5 mg/mL sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2536249 |
Product Specific Information
This product is recommended as a capture antibody in Sandwich ELISA applications.
Target Information
Interleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes, and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7). The expression of the IL-2 gene in mature thymocytes is monoallelic, representing an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a gene similar to IL-2 in mice leads to an ulcerative colitis-like disease, suggesting an essential role of this gene in the immune response to antigenic stimuli.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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