Thermo Fisher Scientific Connexin 30 Polyclonal Antibody (Z-PP9)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-3 µg/mL

View 13 publications 13 publications

Immunohistochemistry (IHC)

-

View 21 publications 21 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

View 2 publications 2 publications

Immunohistochemistry (Frozen) (IHC (F))

Assay-dependent

View 9 publications 9 publications

Immunohistochemistry - Free Floating (IHC (Free))

-

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

1:100-1:500

View 17 publications 17 publications

ELISA (ELISA)

0.1-1 µg/mL

-

Immunoprecipitation (IP)

-

View 1 publication 1 publication

Miscellaneous PubMed (Misc)

-

View 9 publications 9 publications

Product Specifications

Species Reactivity

Cat, Human, Mouse, Rat

Published species

Cat, Chicken, Human, Mouse, Non-human primate, Rat, Xenopus

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Clone

Z-PP9

Immunogen

A synthetic peptide derived from the unique C-terminus of the mouse Connexin 30 protein if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Connexin 30,uniProtId:P70689-1,ncbiNodeId:10090,antigenRange:261,antigenLength:261,antigenImageFileName:71-2200_Connexin_30_P70689-1_Rabbit.svg,antigenImageFileNamePDP:71-2200_Connexin_30_P70689-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.25 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

0.1% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2533979

Product Specific Information

This antibody is specific for the Connexin 30. Cross-reactivity with the highly related Connexin 26 protein or with other Connexin family members has not been detected. Reactivity of this antibody has been confirmed by western blotting using cell lysates derived from adult rat, mouse, human, and cat brains.

Target Information

Gap junctions allow the transport of ions and metabolites between the cytoplasm of adjacent cells. They are formed by two hemichannels, made up of six connexin proteins assembled in groups. Each connexin protein has four transmembrane segments, two extracellular loops, a cytoplasmic loop formed between the two inner transmembrane segments, and the N- and C-terminus both being in the cytoplasm. The specificity of the gap junction is determined by which connexin proteins comprise the hemichannel. In the past, connexin protein names were based on their molecular weight, however the new nomenclature uses sequential numbers based on which form of the gap junction is present. This gene encodes one of the connexin proteins. Mutations in this gene have been found in some forms of deafness and in some families with hidrotic ectodermal dysplasia.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.