Thermo Fisher Scientific FAM111B Polyclonal Antibody
FAM111B 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC(P), ICC/IF에 사용 가능. 사람 및 마우스 반응성. 고순도 친화 크로마토그래피 정제. PBS/glycerol buffer에 보관하며 -20°C에서 안정적 저장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human FAM111B (Accession Q6SJ93), corresponding to amino acid residues L44–R94 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852678 |
Product Specific Information
Antibody detects endogenous levels of total FAM111B.
Target Information
FAM111B is a 734 amino acid protein encoded by a gene on human chromosome 11, which constitutes about 4% of human genomic DNA and is rich in gene–disease associations. Chromosome 11 genes are involved in regulation of cell cycle arrest and apoptosis following DNA damage. Mutations in ATM cause ataxia-telangiectasia; HBB mutations lead to sickle cell anemia and beta-thalassemia; WT1 mutations are linked to Wilms’ tumor, WAGR syndrome, and Denys-Drash syndrome. Other disorders associated with chromosome 11 defects include Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema, and Smith-Lemli-Opitz syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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