Thermo Fisher Scientific H3K23ac Polyclonal Antibody
H3K23ac에 특이적인 Rabbit Polyclonal 항체로, Western blot 및 Immunocytochemistry에 적합. 인간, 마우스, 랫트 시료 반응성. Affinity chromatography로 정제된 액상형 제품이며 -20°C에서 보관. 연구용으로만 사용 가능.
- 카탈로그번호
- PA599333
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human Histone H3 (Accession P68431), corresponding to amino acid residues K5–R27 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818266 |
Product Specific Information
This antibody detects endogenous levels of Acetyl-Histone H3 only when acetylated at Lys23.
Target Information
Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3, along with four core histone proteins, binds to DNA to form the nucleosome structure. Histones play a central role in transcription regulation, DNA repair, DNA replication, and chromosomal stability.
Post-translational modifications of histones, such as methylation, acetylation, and phosphorylation, influence chromatin structure and transcription factor binding. The N-terminal tail of histone H3 can undergo various modifications that regulate key cellular processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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