Thermo Fisher Scientific ICOS Monoclonal Antibody (OTI14C7)
Human ICOS(CD278) 단백질을 인식하는 mouse IgG1 단일클론 항체로, Flow Cytometry에 적합합니다. 무보존제, 동결건조 형태이며 PBS+trehalose buffer에 보관합니다. 연구용으로 세포 신호 및 면역 반응 분석에 활용됩니다.
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Applications
- Flow Cytometry (Flow): Tested dilution 1:100–1:400
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI14C7 |
| Immunogen | Full-length human recombinant ICOS (NP_036224) produced in 293F cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve approximately 1 mg/mL antibody concentration.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
ICOS (CD278) encodes a protein belonging to the CD28 and CTLA-4 receptor family.
It functions as a homodimer, playing a critical role in cell-cell signaling, immune response regulation, and cell proliferation.
Mutations or dysfunctions in ICOS are associated with Common Variable Immunodeficiency (CVID) and related immune disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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