Thermo Fisher Scientific ICOS Monoclonal Antibody (OTI14C8)
ICOS (CD278) 단백질을 인식하는 Mouse IgG1 단클론 항체로, Flow Cytometry에 적합합니다. 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도로 사용 가능합니다. 친화 크로마토그래피로 정제되었으며, 연구용으로만 사용됩니다.
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Applications
- Flow Cytometry (Flow): 1:100–1:400
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI14C8 |
| Immunogen | Full length human recombinant protein of human ICOS (NP_036224) produced in 293F cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882) to ensure carrier-free conditions.
Target Information
ICOS (CD278) encodes a protein belonging to the CD28 and CTLA-4 cell-surface receptor family.
It functions as a homodimer and plays an essential role in cell-cell signaling, immune response regulation, and cell proliferation.
Mutations or dysregulation of ICOS are associated with disorders such as Immunodeficiency, Common Variable, 1 and Common Variable Immunodeficiency.
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
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