Thermo Fisher Scientific XRCC2 Polyclonal Antibody
Human XRCC2 단백질을 인식하는 Rabbit Polyclonal 항체입니다. IHC(P)에서 1:200 희석으로 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. DNA 손상 복구 연구 및 XRCC2 관련 세포 안정성 연구에 적합합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide from the N-terminus of human XRCC2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.6, with 1% BSA |
| Contains | <0.1% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550106 |
Product Specific Information
- Heat-mediated antigen retrieval is recommended prior to staining, using a 10 mM citrate buffer (pH 6.0) for 10 minutes followed by cooling at room temperature for 20 minutes.
- Following antigen retrieval, incubate samples with primary antibody for 10 minutes at room temperature.
- Suggested positive control: testis tissue.
Target Information
The x-ray repair cross-complementing (XRCC) proteins are responsible for efficiently repairing and maintaining genetic stability following DNA base damage. These genes share sequence similarity with the yeast DNA repair protein Rad5.
XRCC2 and XRCC3 are both involved in maintaining chromosome stability during cell division. XRCC2 is required for efficient repair of DNA double-strand breaks by homologous recombination between sister chromatids, and XRCC3 interacts directly with Rad51 to cooperate with Rad51 during recombinational repair.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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