
Thermo Fisher Scientific SARS-CoV-2 Spike Protein S1 Recombinant Rabbit Monoclonal Antibody (HL6)
SARS-CoV-2 Spike Protein S1을 특이적으로 인식하는 recombinant rabbit monoclonal antibody. WB, IHC, ICC, Flow, ELISA 등 다양한 응용 가능. SARS-CoV 및 MERS-CoV와 교차 반응 없음. Protein A로 정제된 고순도 항체로 연구용에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:10,000 | View 1 publication |
| Immunohistochemistry (IHC) | – | View 5 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | – |
| Flow Cytometry (Flow) | Assay-dependent | – |
| ELISA | Assay-dependent | – |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Virus |
| Published Species | Human, Virus |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | HL6 |
| Immunogen | Recombinant protein encompassing a sequence within the N-terminus region of SARS-CoV-2 (COVID-19) spike (S1). The exact sequence is proprietary. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2890589 |
Product Specific Information
Specificity: This antibody detects SARS-CoV-2 Spike protein, but does not cross-react with SARS-CoV or MERS-CoV spike proteins based on internal testing.
Target Information
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2), also known as 2019-nCoV (2019 Novel Coronavirus), causes illnesses ranging from mild cold symptoms to severe respiratory distress and death.
The Spike Protein consists of S1 and S2 domains and serves as the main surface antigen of the coronavirus.
The glycosylated Spike protein can be detected in infected cell culture supernatants with antisera from SARS patients.
The S1 domain contains a receptor-binding domain (RBD) that specifically binds to angiotensin-converting enzyme 2 (ACE2) on target cells.
Spike protein diversity reflects differences in receptor interactions and fusion responses among coronaviruses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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