Thermo Fisher Scientific IL15RA Polyclonal Antibody
IL15RA에 특이적인 Thermo Fisher Scientific의 Goat Polyclonal Antibody로, WB, IHC, ICC, Flow, Neutralization 등 다양한 응용 가능. 인간 IL-15RA에 반응하며, 항원 친화 크로마토그래피로 정제된 무보존제 제품. 연구용으로만 사용.
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Thermo Fisher Scientific IL15RA Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–15 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–15 µg/mL |
| Flow Cytometry (Flow) | 2.5 µg per million cells |
| Neutralization (Neu) | 1–4 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Sf21-derived recombinant human IL-15 R alpha (Ile31–Thr172) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2607948 |
Product Specific Information
- In direct ELISAs, less than 10% cross-reactivity with recombinant human IL-2 R gamma is observed.
- Reconstitute at 0.2 mg/mL in sterile PBS.
- Endotoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
Target Information
Interleukin 15 receptor alpha (IL-15RA) specifically binds IL-15 with high affinity. IL-15 regulates T and NK cell activation and proliferation. IL-15 and IL-2 receptors share IL-2Rβ and IL-2Rγ subunits, while IL-15RA is structurally related to IL-2RA, an IL-2-specific alpha subunit. Unlike IL-2RA, IL-15RA binds IL-15 independently of other subunits and enhances cell proliferation and expression of apoptosis inhibitors Bcl-xL and Bcl-2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-46991_IL15RA_Q13261-1_Goat.svg, PA5-46991_IL15RA_Q13261-1_Goat_PDP.jpeg)
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