Thermo Fisher Scientific NTH1 Polyclonal Antibody, Biotin
Thermo Fisher Scientific의 NTH1 Polyclonal Antibody, Biotin은 인간 NTHL1 단백질을 인식하는 토끼 유래 IgG 폴리클로날 항체입니다. Western blot, ELISA, Immunoprecipitation에 사용 가능하며, Biotin으로 표지되어 높은 특이성과 감도를 제공합니다. 연구용으로만 사용됩니다.
- 카탈로그번호
- NTHL1-110BIOTIN
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific NTH1 Polyclonal Antibody, Biotin
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | C-epitope synthetic peptide within amino acid region 190–290 of human NTHL1 protein |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer (pH 7.4–7.8) with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Oxygen radicals damage chromosomal DNA, causing cell death and mutations. While repair of 8-oxo-G has been a major focus, many other damaged DNA sites are generated by free-radical attacks. The human NTH1 repair protein acts on a wide range of these oxidatively damaged DNA sites. As a homologue of E. coli Endonuclease III, NTH is a DNA glycosylase with apurinic/apyrimidinic lyase activity. It exhibits broad substrate specificity, including numerous ring saturation and fragmentation products of pyrimidines. Research indicates that NTH plays a crucial role in removing oxidative base lesions in mitochondrial DNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일: NTHL1-110-BIOTIN_NTHL1_P78549-1_Rabbit.svg, NTHL1-110-BIOTIN_NTHL1_P78549-1_Rabbit_PDP.jpeg)
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