Thermo Fisher Scientific Neurotrypsin Polyclonal Antibody
Rabbit 유래의 Polyclonal 항체로, 인간 Neurotrypsin 단백질을 인식합니다. CNS 관련 연구에 적합하며, 신경 발달 및 시냅스 가소성 연구에 활용됩니다. 비결합형 액상 제품으로, 단기 4°C, 장기 -20°C 보관 권장.
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Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human Neurotrypsin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Lot-Specific |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2644636 |
Product Specific Information
Immunogen sequence:
GTVEVYASGV WGTVCSSHWD DSDASVICHQ LQLGGKGIAK QTPFSGLGLI PIYWSNVRCR GDEENILLCE KDIWQGGVCP QKMAAAVTCS FS
Sequence identity:
Highest antigen sequence identity to the following orthologs:
- Mouse: 42%
- Rat: 43%
Target Information
Neurotrypsin is a central nervous system-expressed serine protease whose truncation or absence causes nonsyndromic mental retardation. It is most prominently expressed in structures involved in the processing and storage of learned behavior and memory, such as the cerebral cortex, hippocampus, and amygdala. Evidence suggests that neurotrypsin has multiple functions, including axonal outgrowth, maintaining neuronal plasticity, and arranging the perineuronal environment, partly in coordination with other proteases including tissue plasminogen activator. At least two isoforms of neurotrypsin are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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