Thermo Fisher Scientific Neurotrypsin Polyclonal Antibody
Human Neurotrypsin을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 등에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 제품이며, 0.2 mg/mL 농도로 PBS와 40% glycerol에 보존. 신경 가소성과 기억 관련 연구에 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human Neurotrypsin. Recombinant protein control fragment (Product #RP-102646). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2644637 |
Product Specific Information
- Immunogen sequence:
WVSVTDFGAP CLRWAEVPPF LERSPPASWA QLRGQRHNFC RSPDGAGRPW CFYGDARGKV DWGYCDCRHG SVRLRGGK - Highest antigen sequence identity to orthologs:
- Mouse: 71%
- Rat: 72%
Target Information
Neurotrypsin is a central nervous system-expressed serine protease whose truncation or absence causes nonsyndromic mental retardation. It is most prominently expressed in structures involved in processing and storage of learned behavior and memory, such as the cerebral cortex, hippocampus, and amygdala. Evidence suggests that neurotrypsin has multiple functions, including axonal outgrowth, maintaining neuronal plasticity, and arranging the perineuronal environment, partly in coordination with other proteases including tissue plasminogen activator.
At least two isoforms of neurotrypsin are known to exist.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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