Thermo Fisher Scientific GRB14 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human GRB14. Recombinant protein control fragment (Product #RP-102645). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GRB14,uniProtId:Q14449-1,ncbiNodeId:9606,antigenRange:83-172,antigenLength:540,antigenImageFileName:PA5-57131_GRB14_Q14449-1_Rabbit.svg,antigenImageFileNamePDP:PA5-57131_GRB14_Q14449-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.08 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2642206

Product Specific Information

Immunogen sequence: PELCCSPFTS VLSADLFPKA NSRKKQVIKV YSEDETSRAL DVPSDITARD VCQLLILKNH YIDDHSWTLF EHLPHIGVER TIEDHELVIE

Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 81%.

Target Information

The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. This protein likely has an inhibitory effect on receptor tyrosine kinase signaling and, in particular, on insulin receptor signaling. This gene may play a role in signaling pathways that regulate growth and metabolism. Transcript variants have been reported for this gene, but their full-length natures have not been determined to date.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.