Thermo Fisher Scientific GRB14 Polyclonal Antibody
Rabbit polyclonal antibody against human GRB14 단백질로 IHC(P)에서 1:50–1:200 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS, 40% glycerol 용액에 보관. 인슐린 수용체 신호 조절 연구에 적합.
- 카탈로그번호
- PA557131
- 판매단위
- pk
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Applications
Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human GRB14. Recombinant protein control fragment (Product # RP-102645) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.08 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2642206 |
Product Specific Information
Immunogen sequence:
PELCCSPFTS VLSADLFPKA NSRKKQVIKV YSEDETSRAL DVPSDITARD VCQLLILKNH YIDDHSWTLF EHLPHIGVER TIEDHELVIE
Antigen sequence identity:
- Mouse: 88%
- Rat: 81%
Target Information
The product of this gene belongs to a small family of adapter proteins that interact with receptor tyrosine kinases and signaling molecules. It encodes a growth factor receptor-binding protein that interacts with insulin and insulin-like growth factor receptors, likely inhibiting receptor tyrosine kinase signaling, particularly insulin receptor signaling. This gene may play a role in pathways regulating growth and metabolism. Transcript variants have been reported, though their full-length forms are not yet determined.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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