Thermo Fisher Scientific VE-cadherin Monoclonal Antibody (BV9), FITC
VE-cadherin 단백질의 EC3-EC4 영역을 인식하는 BV9 클론 단일클론 항체로, FITC 형광 표지. WB, IHC, ICC, Flow 등 다양한 응용에 사용 가능. 액상 형태로 4°C 암소 보관. 연구용으로만 사용.
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Thermo Fisher Scientific VE-cadherin Monoclonal Antibody (BV9), FITC
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:50 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:50 |
| Flow Cytometry (Flow) | 1:50 |
| Immunoprecipitation (IP) | 1:50 |
| Functional Assay | 1:50 |
| Inhibition Assays (IA) | 1:50 |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | BV9 |
| Immunogen | The monoclonal antibody BV9 binds to the extracellular domain (EC3–EC4) of human VE-cadherin (vascular endothelial cadherin). |
| Conjugate | FITC (Fluorescein) |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 100 µg/mL |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Wet ice |
| RRID | AB_3093255 |
Target Information
VE-cadherin is a member of the cadherin superfamily located on chromosome 16. It plays a critical role in endothelial cell biology by mediating calcium-dependent cell-cell adhesion and maintaining intercellular junction integrity. VE-cadherin consists of five extracellular cadherin repeats, a transmembrane region, and a conserved cytoplasmic tail. It is implicated in tumorigenesis through loss of heterozygosity events in breast and prostate cancer. An alternative splice variant has been described, though the full-length sequence has not been fully determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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