Thermo Fisher Scientific CD96 Monoclonal Antibody (NK92.39)
인간 CD96 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Flow Cytometry 및 Functional Assay에 적합. NK92 세포의 PVR 결합을 차단하며, 단백질 G 정제 및 PBS/BSA 용액 형태로 제공. 연구용으로만 사용 가능.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 1:50
Functional Assay (Functional)
- Tested Dilution: 1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | NK92.39 |
| Immunogen | The monoclonal antibody NK92.39 reacts with CD96 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 100 µg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 0.1% BSA |
| Contains | No preservative |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
| RRID | AB_3091103 |
Product Specific Information
The monoclonal antibody NK92.39 blocks binding of soluble poliovirus receptor (PVR) to NK92 cells.
Target Information
CD96 is a cell adhesion receptor also known as TACTILE. A member of the Ig superfamily, CD96 is a single-pass transmembrane protein consisting of three extracellular Ig-like domains and a proline/serine/threonine-rich region.
CD96 is expressed on resident monocytes and T cells at all developmental stages (including gamma-delta T cells, thymocytes, and NK cells).
In the mouse, this receptor is not expressed on B cells. Unlike in humans, mouse CD96 does not exist as alternative splice variants.
Reports indicate that CD96 binds CD155/poliovirus receptor and Nectin-1 to mediate NK cell adhesion to target cells and cytotoxicity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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