Thermo Fisher Scientific Properdin Monoclonal Antibody (1G6D2)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:50

-

Functional Assay (Functional)

1:50

-

Inhibition Assays (IA)

1:50

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

1G6D2

Immunogen

Human properdin purified from human plasma. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Properdin,uniProtId:P27918-1,ncbiNodeId:9606,antigenRange:1-469,antigenLength:469,antigenImageFileName:MA5-49026_Properdin_P27918-1_House_mouse.svg,antigenImageFileNamePDP:MA5-49026_Properdin_P27918-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

100 µg/mL

Purification

Protein G

Storage buffer

PBS with 0.1% BSA

Contains

no preservative

Storage conditions

4° C

Shipping conditions

Wet ice

RRID

AB_3091112

Target Information

This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.