Thermo Fisher Scientific TRIF Polyclonal Antibody
TRIF 단백질을 검출하기 위한 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, ICC/IF, IP 등 다양한 응용 가능. 0.5 mg/mL 농도의 액상 형태로 제공되며, 4°C 또는 -20°C에서 안정적으로 보관 가능. 연구용으로만 사용.
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Thermo Fisher Scientific TRIF Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:10–1:100 |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 143–158 of Mouse TRIF |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2303858 |
Product Specific Information
By Western blot, PA1-20824 detects the ~66 kDa TRIF protein.
Target Information
TRIF is involved in innate immunity against invading pathogens. It acts as an adapter used by TLR3 and TLR4 (through TICAM2) to mediate NF-kappa-B and interferon-regulatory factor (IRF) activation, and to induce apoptosis. Ligand binding to these receptors results in TRIF recruitment through its TIR domain. Distinct protein-interaction motifs allow recruitment of effector proteins TBK1, TRAF6, and RIPK1, which lead to activation of transcription factors IRF3, IRF7, NF-kappa-B, and FADD respectively.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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