Thermo Fisher Scientific CRP Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Recommended positive controls: Testing antigen control, pooled pre-immune background control, and an optional positive assay control kit.
• Store product as a concentrated solution.
• Centrifuge briefly prior to opening the vial.

Target Information

C-reactive protein (CRP) is a major cyclic, pentameric acute phase protein composed of five identical, noncovalently bound, nonglycosylated subunits. Each subunit consists of 206 amino acids with a molecular weight of approximately 24 kDa.
CRP is synthesized by the liver, and its plasma concentration increases dramatically during inflammation, infection, or injury—up to 100–1000 fold.
It functions as an initiator of the classical complement cascade, binds to nuclear components such as chromatin and histones, and plays a critical role in innate immunity and host defense.
Elevated basal levels of CRP are associated with increased risk of hypertension and cardiovascular disease.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.