Thermo Fisher Scientific Cytokeratin 8 (KRT8) Recombinant Rabbit Monoclonal Antibody (KRT8/6472R)
Recombinant rabbit monoclonal antibody against human Cytokeratin 8 (KRT8), validated for WB and IHC applications. High specificity and purity via Protein A/G purification. Supplied as liquid, unconjugated form, ideal for epithelial cell research.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2 µg/mL |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | KRT8/6472R |
| Immunogen | Recombinant full-length human KRT8 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Target Information
Cytokeratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. Cytokeratin 8 typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: 3856-RBM22-P1ABX_Cytokeratin_8_P05787-1_Rabbit.svg, 3856-RBM22-P1ABX_Cytokeratin_8_P05787-1_Rabbit_PDP.jpeg)
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