Thermo Fisher Scientific Periostin Monoclonal Antibody (OTI2D10), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000

Product Specifications

Additional Formats

• Biotin Conjugated Version
• Request Custom Conjugation

Product Specific Information

For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

Periostin (PN), also known as osteoblast-specific factor 2 (OSF-2), is a disulfide-linked, secreted protein that binds heparin and functions as a ligand for integrins αVβ3 and αVβ5. It acts as a cell adhesion molecule in preosteoblasts, playing roles in osteoblast recruitment, spreading, and attachment.
Periostin is mainly expressed in the gastrointestinal tract, aorta, stomach, placenta, uterus, and breast tissues, but is upregulated in epithelial ovarian tumors and overexpressed in breast cancer.
Expression is induced by BMP2 and TGF-β1. The protein includes a signal sequence, a cysteine-rich domain, four fasciclin-like repeats, and a C-terminal domain.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.