
Thermo Fisher Scientific Inhibin, alpha (INHA) (Gonadal Cell Marker) Monoclonal Antibody (R1)
인히빈 알파(INHA) 단일클론 항체로 인간 시료에 반응하며, IHC(P) 및 IHC(PFA) 실험에 적합합니다. 단백질 A/G로 정제된 액상 항체로, 1 mg/mL 농도이며 PBS(pH 7.4)에 보존제를 포함하지 않습니다. 생식세포 마커 연구용으로 사용됩니다.
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Thermo Fisher Scientific Inhibin, alpha (INHA) (Gonadal Cell Marker) Monoclonal Antibody (R1)
Applications
- Immunohistochemistry (Paraffin) (IHC (P)): Assay-dependent
- Immunohistochemistry (PFA fixed) (IHC (PFA)): 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | R1 |
| Immunogen | Synthetic peptide corresponding to Human Inhibin alpha aa 233–264 (N-terminus of mature region) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The inhibin alpha subunit joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin negatively regulates gonadal stromal cell proliferation and exhibits tumor-suppressor activity. Serum levels of inhibin reflect granulosa-cell tumor size and serve as a marker for primary and recurrent disease. In prostate cancer, inhibin alpha-subunit gene expression is suppressed and undetectable in poorly differentiated tumor cells. Expression varies among gonadal and extragonadal tissues, suggesting inhibin functions as both a growth/differentiation factor and a hormone.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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