
Thermo Fisher Scientific Inhibin, alpha (INHA) Recombinant Rabbit Monoclonal Antibody (INHA, 6598R)
Recombinant rabbit monoclonal antibody specific for human Inhibin alpha (INHA). Optimized for IHC (paraffin) applications. Provides high specificity and reproducibility. Supplied as a liquid at 200 µg/mL in PBS with BSA and sodium azide. For research u...
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | INHA, 6598R |
| Immunogen | Recombinant fragment of human Inhibin alpha protein (around aa 233–362) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For immunohistochemistry (PFA fixed): incubate antibody for 30 minutes at room temperature.
Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA (pH 9.0) for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
The inhibin alpha subunit combines with either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin negatively regulates gonadal stromal cell proliferation and exhibits tumor-suppressor activity. Serum inhibin levels correlate with granulosa-cell tumor size, making it a useful marker for primary and recurrent disease. In prostate cancer, inhibin alpha-subunit gene expression is suppressed and undetectable in poorly differentiated tumor cells. Expression varies among tissues, suggesting inhibin functions as both a growth/differentiation factor and a hormone.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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