Thermo Fisher Scientific Inhibin, alpha (INHA) (Gonadal Cell Marker) Monoclonal Antibody (rINHA/6919)
사람 Inhibin α 단백질을 인식하는 단클론 항체로, 생식세포 표지자 연구에 적합합니다. 파라핀 포매 및 PFA 고정 조직의 면역조직화학(IHC)에 사용됩니다. 단백질 A/G로 정제된 액상 형태이며, -20°C에서 보관합니다.
- 카탈로그번호
- 3623-MSM9-P1ABX
- 판매단위
- pk
카탈로그
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 2 µg/mL
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | rINHA/6919 |
| Immunogen | Recombinant fragment of human Inhibin alpha protein (around aa 233–362) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The inhibin alpha subunit joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin negatively regulates gonadal stromal cell proliferation and exhibits tumor-suppressor activity. Serum levels of inhibin reflect the size of granulosa-cell tumors, serving as a marker for both primary and recurrent disease. In prostate cancer, expression of the inhibin alpha-subunit gene is often suppressed and undetectable in poorly differentiated tumor cells. Because expression varies across gonadal and extragonadal tissues, inhibin may function as both a growth/differentiation factor and a hormone.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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