Thermo Fisher Scientific NFATC1 Recombinant Rabbit Monoclonal Antibody (JA81-03)
NFATC1 단백질을 인식하는 재조합 토끼 단클론 항체. Western blot, IHC, Flow Cytometry에 적합. 높은 특이성과 재현성을 제공하며, lot 간 일관성이 우수. 단백질 A 정제, 액상 형태로 제공되며, 4°C 단기 보관 및 -20°C 장기 보관 권장.
- 카탈로그번호
- MA532686
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific NFATC1 Recombinant Rabbit Monoclonal Antibody (JA81-03)
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:1,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Flow Cytometry (Flow) | 1:1000 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JA81-03 |
| Immunogen | Synthetic peptide within Human NFAT2 aa 894–943 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809963 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. These systems use cloned antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages include:
- Improved specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
The NFATC1 gene encodes a component of the nuclear factor of activated T cells (NFAT) DNA-binding transcription complex. This complex includes:
- A cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation
- An inducible nuclear component
NFAT family proteins play a central role in inducible gene transcription during immune responses.
NFATC1 functions as a major molecular target for immunosuppressive drugs such as cyclosporin A.
Five transcript variants encoding distinct isoforms have been identified, which may regulate inducible expression of different cytokine genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.