Thermo Fisher Scientific LPL Recombinant Rabbit Monoclonal Antibody (JA22-02)
LPL 단백질을 인식하는 재조합 토끼 단일클론 항체로, 높은 특이성과 재현성을 제공합니다. Western blot 및 IHC(파라핀 포함)에 적합하며, HEK293 세포에서 발현된 IgG 형 항체입니다. 단백질 A로 정제되어 안정적인 액상 형태로 제공됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunohistochemistry (IHC)
- Tested Dilution: Not specified
- Publication: 1 available
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JA22-02 |
| Immunogen | Synthetic peptide within Human Lipoprotein lipase (aa 456–475) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809965 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned and screened to select optimal production candidates. Advantages include:
- High specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broad immunoreactivity due to large rabbit immune repertoire
Target Information
LPL encodes lipoprotein lipase, expressed in heart, muscle, and adipose tissue. It functions as a homodimer with dual roles:
- Triglyceride hydrolase activity
- Ligand/bridging factor for receptor-mediated lipoprotein uptake
Mutations causing LPL deficiency lead to type I hyperlipoproteinemia, while milder mutations are linked to various lipoprotein metabolism disorders.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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