Thermo Fisher Scientific GNB5 Polyclonal Antibody
GNB5 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, Western blot, IHC, Flow cytometry에 적합합니다. 인간, 마우스, 랫트에 반응하며, 항원 친화 정제된 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein within human Gbeta5 (aa 1–200) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.4, with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2913552 |
Product Specific Information
- Positive Control: HepG2 cell lysate, mouse brain tissue lysate, rat brain tissue lysate, rat brain tissue, HeLa cells
- Subcellular Location: Membrane
Target Information
The Gb5 protein is a G protein subunit predominantly present in the central nervous system. Two forms are expressed: a 39 kDa form in the brain and a 44 kDa form in the retina. Gb5 associates tightly with RGS7, a member of the superfamily of negative regulators of G protein signaling. These complexes are localized to most regions of the brain, whereas Gb1–4 show no observable colocalization with RGS7 despite their widespread codistribution. This antibody is specific for a peptide sequence within the D1 blade, which is not found in Gb1–4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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