Thermo Fisher Scientific Cytokeratin 5/6 Polyclonal Antibody
Human Cytokeratin 5/6을 인식하는 Rabbit Polyclonal Antibody로, WB 및 IHC(P) 분석에 적합. 고순도 Affinity Chromatography 정제, 1 mg/mL 농도. 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:600 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within human Cytokeratin 5 (aa 191–240) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | TBS, pH 7.4, with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2913549 |
Product Specific Information
- Positive Control: Human skin tissue lysate, A431 cell lysate, human tonsil tissue, human lung adenocarcinoma tissue
- Subcellular Location: Intermediate filament, Keratin
Target Information
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues.
This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12–q13.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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