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Thermo Fisher Scientific Human LRRK2 [G2019S], GST Tag Recombinant Protein

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인간 LRRK2 G2019S 변이 GST 태그 재조합 단백질로 파킨슨병 연구용 키나아제 분석에 적합. 곤충세포 발현, 고순도 정제, -80°C 보관. 연구 전용 제품으로 안정적 활성 유지 및 다양한 키나아제 분석에 활용 가능.

브랜드: Thermo Fisher Scientific
카테고리: Protein
판매단위: pk

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Thermo Fisher Scientific PR8764C Human LRRK2 [G2019S], GST Tag Recombinant Protein 100 ug pk판매 단위 pk ·

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Thermo Fisher Scientific · Thermo Fisher Scientific Human LRRK2 [G2019S], GST Tag Recombinant Protein

Thermo Fisher Scientific Human LRRK2 [G2019S], GST Tag Recombinant Protein

Applications

Kinase Assay (KA)

Tested Dilution: Assay-dependent
Publications: -

Product Specifications

항목	내용
Species	Human
Expression System	Insect cells
Amino Acid Sequence	970-2527; G2019S
Tag	GST-tag
Molecular Weight	204.9 kDa
Class	Recombinant
Type	Protein
Conjugate	Unconjugated
Form	Liquid
Concentration	See Label
Purification	Purified
Storage Buffer	50 mM Tris, pH 7.5, with 0.02% polysorbate 20, 50% glycerol, 0.5 mM EDTA, 150 mM NaCl, 2 mM DTT
Contains	No preservative
Storage Conditions	-80°C, Avoid Freeze/Thaw Cycles
Shipping Conditions	Dry ice

Product Specific Information

For maximum recovery, please spin prior to use.
Aliquots of the 5 µg, 10 µg, and 20 µg sizes are not recommended; use in original packaging until exhausted.
For larger sizes, aliquot preparation may reduce freeze/thaw cycles (avoid aliquots below 20 µL).
Do not store kinase diluted.
Properly stored at -80°C, product is guaranteed for 6 months from date of purchase.

Protein Form: Recombinant, Catalytic, Mutant

Target Information

LRRK2 (Leucine Rich Repeat Kinase 2) is a protein-coding gene.
Diseases associated with LRRK2 include Parkinson Disease 8 (Autosomal Dominant) and Hereditary Late-Onset Parkinson Disease.
Related pathways include:

Signaling by PTK6
ncRNAs involved in Wnt signaling in hepatocellular carcinoma

Gene Ontology (GO) annotations:

Protein homodimerization activity
Transferase activity (transferring phosphorus-containing groups)

An important paralog of LRRK2 (G2019S Mutant) is TNNI3K.
Mutations in the LRRK2 gene are known as the most common genetic cause of late-onset autosomal-dominant Parkinson’s disease.