Thermo Fisher Scientific LCAT Polyclonal Antibody
Thermo Fisher Scientific의 LCAT Polyclonal Antibody는 인간 및 마우스 반응성을 가지며 Western Blot과 ELISA에 사용됩니다. Rabbit IgG 폴리클로날 항체로, 비결합형 액상 형태이며 CHO 세포에서 정제된 인간 LCAT 항원을 면역원으로 사용합니다. 연구용으로 HDL 관련 콜레스테롤 대사 연구에 적합합니다.
- 카탈로그번호
- PA316791
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- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
ELISA
- Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Carboxyl-terminal histidine-tagged human recombinant LCAT purified from the medium of CHO cells overexpressing human LCAT cDNA |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2136047 |
Product Specific Information
Suggested positive control: antigen standard for LCAT (transient overexpression lysate), Lipoprotein fraction of whole human plasma.
Target Information
Lecithin: cholesterol acyltransferase (LCAT) is a plasma enzyme responsible for most HDL cholesteryl esters in human plasma. In species with cholesteryl ester transfer protein (CETP), it also contributes to VLDL and LDL cholesteryl ester formation.
LCAT plays a key role in reverse cholesterol transport by facilitating cholesterol movement from peripheral tissues to the liver for excretion.
LCAT deficiency leads to low plasma HDL levels, while transgenic overexpression increases plasma HDL concentrations.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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