Thermo Fisher Scientific LCAT Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:1,000

ELISA

• Tested Dilution: 1:500

Product Specifications

Product Specific Information

Suggested positive control: antigen standard for LCAT (transient overexpression lysate), Lipoprotein fraction of whole human plasma.

Target Information

Lecithin: cholesterol acyltransferase (LCAT) is a plasma enzyme responsible for most HDL cholesteryl esters in human plasma. In species with cholesteryl ester transfer protein (CETP), it also contributes to VLDL and LDL cholesteryl ester formation.
LCAT plays a key role in reverse cholesterol transport by facilitating cholesterol movement from peripheral tissues to the liver for excretion.
LCAT deficiency leads to low plasma HDL levels, while transgenic overexpression increases plasma HDL concentrations.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.