Thermo Fisher Scientific SR-BI Polyclonal Antibody
SR-BI 단백질을 검출하기 위한 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC 등 다양한 실험에 사용 가능. 인간, 마우스, 랫트 반응성. 고품질 비결합 항체로 콜레스테롤 대사 연구에 적합.
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Thermo Fisher Scientific SR-BI Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-Dependent |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | Assay-Dependent |
| Immunoprecipitation (IP) | 1:100 |
| Neutralization (Neu) | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Adenovirus encoding mSR-BI |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2182693 |
Target Information
High density lipoproteins (HDLs) play a critical role in cholesterol metabolism, and their plasma concentrations are inversely correlated with risk for atherosclerosis.
The SR-BI binds HDLs and mediates selective uptake of HDL cholesteryl ester. It binds HDL with high affinity, is expressed primarily in liver and nonplacental steroidogenic tissues, and mediates selective cholesterol uptake by a distinct mechanism.
In mice, SR-BI plays a key role in determining plasma lipoprotein cholesterol levels and cholesterol accumulation in the adrenal gland.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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