Thermo Fisher Scientific NR5A2/LRH1 Monoclonal Antibody (PCRP-NR5A2-1B8)

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1-2 µg/mL

-

Flow Cytometry (Flow)

1-2 µg/mL

-

Peptide Array (Array)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

PCRP-NR5A2-1B8

Immunogen

Recombinant human NR5A2 protein if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:NR5A2,uniProtId:O00482-1,ncbiNodeId:9606,antigenRange:1-541,antigenLength:541,antigenImageFileName:2494-MSM2-P0_NR5A2_O00482-1_House_mouse.svg,antigenImageFileNamePDP:2494-MSM2-P0_NR5A2_O00482-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

200 µg/mL

Purification

Protein A/G

Storage buffer

PBS with 0.05% BSA

Contains

0.05% sodium azide

Storage conditions

4° C

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Positive Control:HeLa or MCF-7 cells.

Cellular Location: Nucleus.

Target Information

Binds to the sequence element 5-AACGACCGACCTTGAG-3 of the enhancer II of hepatitis B virus genes, a critical cis-element of their expression and regulation. May be responsible for the liver-specific activity of enhancer II, probably in combination with other hepatocyte transcription factors. Key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. May also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.