Thermo Fisher Scientific Ferritin, Heavy Chain (FTH) Monoclonal Antibody (FTH, 2082)
Ferritin Heavy Chain(FTH) 단백질을 인식하는 mouse monoclonal 항체로, Western blot 및 IHC(Paraffin)에 적합. Human 시료 반응성. Protein A/G 정제, 200 µg/mL 농도. PBS(pH 7.4)와 0.05% BSA 포함, 4°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2c, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | FTH, 2082 |
| Immunogen | Recombinant human FTH1 protein fragment (around aa 58–180) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed):
Incubate antibody for 30 minutes at room temperature.
For formalin-fixed tissues, heat sections in 10 mM Tris with 1 mM EDTA (pH 9.0) for 45 minutes at 95°C, then cool at room temperature for 20 minutes.
Target Information
FTH1 is the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It consists of 24 subunits of heavy and light ferritin chains. Variation in ferritin subunit composition may affect iron uptake and release rates in different tissues. Ferritin stores iron in a soluble and non-toxic form. Defects in ferritin proteins are linked to several neurodegenerative diseases. This gene has multiple pseudogenes, and several alternatively spliced transcript variants have been observed, though their biological validity remains undetermined.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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