Thermo Fisher Scientific CEACAM1/5 Recombinant Rabbit Monoclonal Antibody (BLR032F)

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-dependent

-

Immunohistochemistry (IHC)

Assay-dependent

-

Immunocytochemistry (ICC/IF)

Assay-dependent

-

Immunoprecipitation (IP)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

HEK293F

Class

Recombinant Monoclonal

Type

Antibody

Clone

BLR032F

Immunogen

Recombinant protein representing the extracellular domain of Human CEACAM1 (residues 35-433) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CEACAM1/CEACAM5,uniProtId:P06731-1,ncbiNodeId:9606,antigenRange:35-433,antigenLength:702,antigenImageFileName:A700-032CF_CEACAM1CEACAM5_P06731-1_Rabbit.svg,antigenImageFileNamePDP:A700-032CF_CEACAM1CEACAM5_P06731-1_Rabbit_PDP.jpeg,sortOrder:1},{targetFamily:CEACAM1/CEACAM5,uniProtId:P13688-1,ncbiNodeId:9606,antigenRange:35-433,antigenLength:526,antigenImageFileName:A700-032CF_CEACAM1CEACAM5_P13688-1_Rabbit.svg,antigenImageFileNamePDP:A700-032CF_CEACAM1CEACAM5_P13688-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

purified

Storage buffer

BBS, pH 8.2

Contains

0.09% sodium azide

Storage conditions

4° C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

Over-expression of CEA/CEACAM5 in tumors of epithelial origin is the basis of its wide-spread use as a tumor marker CEACAM1 expression is down-regulated in many tumors indicating a tumor-suppressive function. The anti-tumor effect may be due to inhibition of tumor angiogenesis, possibly by increased secretion of anti-angiogenic molecules from the cells. The function of CEA family members varies widely: they function as cell adhesion molecules, tumor suppressors, regulators of lymphocyte and dendritic cell activation, receptors of Neisseria species and other bacteria.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.