Thermo Fisher Scientific CEACAM1/5 Recombinant Rabbit Monoclonal Antibody (BLR032F)
CEACAM1/5 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot, IHC, ICC/IF, IP 등 다양한 어플리케이션에 적합. Human 시료 반응성, 고순도 정제, 1 mg/mL 농도, 4°C 보관. 연구용으로만 사용 가능.
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Thermo Fisher Scientific CEACAM1/5 Recombinant Rabbit Monoclonal Antibody (BLR032F)
Applications and Tested Dilution
- Western Blot (WB): Assay-dependent
- Immunohistochemistry (IHC): Assay-dependent
- Immunocytochemistry (ICC/IF): Assay-dependent
- Immunoprecipitation (IP): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | BLR032F |
| Immunogen | Recombinant protein representing the extracellular domain of Human CEACAM1 (residues 35–433) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Purified |
| Storage Buffer | BBS, pH 8.2 |
| Contains | 0.09% Sodium Azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Over-expression of CEA/CEACAM5 in tumors of epithelial origin is the basis of its wide-spread use as a tumor marker.
CEACAM1 expression is down-regulated in many tumors, indicating a tumor-suppressive function. The anti-tumor effect may be due to inhibition of tumor angiogenesis, possibly by increased secretion of anti-angiogenic molecules from the cells.
CEA family members function as cell adhesion molecules, tumor suppressors, regulators of lymphocyte and dendritic cell activation, and as receptors for Neisseria species and other bacteria.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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