Thermo Fisher Scientific PARP1 Monoclonal Antibody (7A10)
PARP1 단백질을 검출하기 위한 Thermo Fisher Scientific의 Mouse Monoclonal Antibody (Clone 7A10). Western blot, Flow cytometry, ELISA에 적합하며 Human 시료에 반응. KLH 결합 합성 펩타이드 면역원 사용, 연구용으로만 제공.
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Thermo Fisher Scientific PARP1 Monoclonal Antibody (7A10)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 7A10 |
| Immunogen | Synthetic peptide of human PARP, conjugated to KLH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10979359 |
Product Specific Information
MA5-15607 targets PARP in indirect ELISA, FACS, and WB applications and shows reactivity with Human samples.
The MA5-15607 immunogen is a synthetic peptide of human PARP conjugated to KLH.
MA5-15607 detects PARP, which has a predicted molecular weight of approximately 117 kDa.
Target Information
Poly ADP-Ribose Polymerase (PARP) uses nicotinamide adenine dinucleotide (oxidized form) NAD as a substrate to catalyze the transfer of ADP-ribose to various nuclear protein acceptors.
Proteolysis of PARP to its stable 85 kDa fragment is an early marker of programmed cell death (apoptosis) and is mediated by the caspase CPP32 protein.
Cleavage occurs between Adp216 and Gly217, a site in PARP conserved across species.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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