Thermo Fisher Scientific TCF3 Monoclonal Antibody (6B8)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Flow Cytometry (Flow)

1:200-1:400

-

ELISA (ELISA)

1:10,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

6B8

Immunogen

Purified recombinant fragment of human TCF3 expressed in E. Coli.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Storage buffer

ascites

Contains

0.03% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_10986881

Product Specific Information

MA5-15603 targets TCF3 in indirect ELISA, FACS and WB applications and shows reactivity with Human samples.

The MA5-15603 immunogen is purified recombinant fragment of human TCF3 expressed in E. Coli.

MA5-15603 detects TCF3 which has a predicted molecular weight of approximately 67.6kDa.

Target Information

TCF3 (E2A) is a transcription factor that plays major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Heterodimers between E2A and tissue-specific basic helix-loop-helix (bHLH) Dimers bind DNA on E-box motifs: 5- CANNTG-3. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer. Deletions in E2A have been observed in a subset of pre-B-cell acute lymphoblastic leukemia (B-ALL) cases. Two alternatively spliced human isoforms have been described.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.