Thermo Fisher Scientific TCF3 Monoclonal Antibody (6B8)
TCF3 단백질을 검출하기 위한 Mouse IgG1 단일클론 항체로, WB, Flow Cytometry, ELISA에 적합합니다. 인간 시료에 반응하며 비접합형 액상 형태로 제공됩니다. 장기 보관 시 -20°C에서 냉동 보관을 권장합니다.
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Thermo Fisher Scientific TCF3 Monoclonal Antibody (6B8)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6B8 |
| Immunogen | Purified recombinant fragment of human TCF3 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Buffer | Ascites |
| Contains | 0.03% Sodium Azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Wet Ice |
| RRID | AB_10986881 |
Product Specific Information
MA5-15603 targets TCF3 in indirect ELISA, FACS, and WB applications, showing reactivity with human samples.
The immunogen is a purified recombinant fragment of human TCF3 expressed in E. coli.
MA5-15603 detects TCF3, which has a predicted molecular weight of approximately 67.6 kDa.
Target Information
TCF3 (E2A) is a transcription factor that plays major roles in determining tissue-specific cell fate during embryogenesis, such as muscle or early B-cell differentiation.
Heterodimers between E2A and tissue-specific basic helix-loop-helix (bHLH) dimers bind DNA on E-box motifs (5'-CANNTG-3').
It binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer.
Deletions in E2A have been observed in a subset of pre-B-cell acute lymphoblastic leukemia (B-ALL) cases.
Two alternatively spliced human isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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