
Thermo Fisher Scientific p70 S6 Kinase Recombinant Superclonal Antibody (15HCLC)
Recombinant Superclonal™ rabbit antibody recognizing human p70 S6 Kinase. Offers high sensitivity and specificity with consistent recombinant production. Suitable for WB, ICC/IF, and ELISA. Predicted cross-reactivity with multiple species.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | Assay-Dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Superclonal |
| Type | Antibody |
| Clone | 15HCLC |
| Immunogen | Peptide corresponding to amino acids 294–306 of human p70 Ribosomal Protein S6 Kinase |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2532663 |
Product Specific Information
This antibody is predicted to react with mouse, rat, non-human primate, and rabbit based on sequence homology.
Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They are composed of multiple different recombinant monoclonal antibodies, combining the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies. Each lot is produced with a known mixture of light and heavy chains, ensuring consistency and eliminating biological variability typical of polyclonal antibody production.
Formerly called “Recombinant polyclonal antibody”, this product is now rebranded as “Recombinant Superclonal™ antibody”. The physical product and performance remain unchanged.
Target Information
RPS6KB1 (p70S6K) is a serine/threonine kinase with two non-identical catalytic domains that phosphorylate residues of the S6 ribosomal protein. Predominantly localized in the cytoplasm, it plays essential roles in growth factor-regulated cell proliferation, motility, immune response, and tissue repair. Acting downstream of PI3-kinase, p70 S6 kinase promotes protein synthesis and cell proliferation. Amplification and overexpression of p70 S6 kinase are observed in certain breast cancer cell lines.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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