ELK Biotechnology hnRNP D0 (phospho Ser83) rabbit pAb
hnRNP D0 (phospho Ser83) rabbit polyclonal antibody for detection of phosphorylated hnRNP D0 in human, mouse, and rat samples. Suitable for WB, IHC, IF, and ELISA. High specificity for Ser83 phosphorylation site. Stable for 1 year at -20°C.
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ELK Biotechnology hnRNP D0 (phospho Ser83) rabbit pAb
제품 개요
hnRNP D0 (phospho Ser83) rabbit polyclonal antibody는 인간 hnRPD 단백질의 Ser83 인산화 부위 주변에서 합성된 펩타이드를 면역원으로 제작되었습니다. 본 항체는 다양한 응용 분야에서 hnRNP D0의 인산화 상태를 검출하는 데 적합합니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | hnRNP D0 (phospho Ser83) rabbit pAb |
| Alternative Names | HNRNPD; AUF1; HNRPD; Heterogeneous nuclear ribonucleoprotein D0; hnRNP D0; AU-rich element RNA-binding protein 1 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500–1/2000 Immunohistochemistry: 1/100–1/300 Immunofluorescence: 1/200–1/1000 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human hnRPD around phosphorylation site of Ser83 (AA range: 49–98) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 38 kD |
| GeneID (Human) | 3184 |
| Human Swiss-Prot No | Q14103 |
| Species Reactivity | Human; Mouse; Rat |
| Cellular Localization | Nucleus; Cytoplasm; Localized in cytoplasmic mRNP granules containing untranslated mRNAs; Component of ribonucleosomes; Cytoplasmic localization oscillates diurnally |
Background
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). These nucleic acid-binding proteins form complexes with heterogeneous nuclear RNA (hnRNA) and are involved in pre-mRNA processing, mRNA metabolism, and transport. Although hnRNPs are primarily nuclear, some shuttle between the nucleus and cytoplasm. The hnRNP D0 protein contains two quasi-RRM domains that bind RNA and localizes to both nucleus and cytoplasm. It plays a role in mRNA stability regulation. Alternative splicing yields four transcript variants.
[provided by RefSeq, Jul 2008]
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