Thermo Fisher Scientific TNFR2 Polyclonal Antibody
Human, Mouse, Rat에 반응하는 Rabbit Polyclonal TNFR2 항체. Western blot과 ELISA에 적합하며, Affinity Chromatography로 정제됨. PBS/glycerol buffer에 보관되며 -20°C에서 안정적. 세포막 및 분비형 단백질 검출용 연구용 시약.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to amino acids 295–377 of human TNFR2/TNFRSF1B (NP_0010571) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.38 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2913678 |
Product Specific Information
Positive test controls include:
- SW620
- Mouse liver
- Mouse spleen
- Rat liver
The target is usually found in:
- Cell membrane
- Secreted
- Single-pass type I membrane protein
Immunogen sequence:
QREAKVPHLP ADKARGTQGP EQQHLLITAP SSSSSSLESS ASALDRRAPT RNQPQAPGVE ASGAGEARAS TGSSDSSPGG HGT
Target Information
TNFR2 (tumor necrosis factor receptor superfamily member 1B) is a receptor with high affinity for TNFSF2/TNF-alpha and lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. TNFR2 mediates most of the metabolic effects of TNF-alpha.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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